Pain is an unpleasant sensation in which an individual is unable to perform day to day activities. It is caused by the damaging stimuli such as stubbing a toe, burning the finger or any other condition. In a recent survey done by American Health Association, it was found that around 50% of the cases coming in the OPD of a hospital are for pain and maximum of them are suffering from the chronic pain. At that very particular time Ultram is the best solution to be considered.
Use Tramadol Ultram 50 mg Tablet to Reduce Body Pain
Ultram with an active ingredient Tramadol is a narcotic like pain reliever which is used for the treatment of moderate to severe pain. Ultram is an extended release tablet that helps in treating the pain which is not relieved by other medicines. Tramadol Ultram 50 mg medication has been in use from long which signifies its effectiveness. This medication is most commonly recommended by doctors worldwide for the treatment of major pain disorders.
How Tramadol Ultram 50 mg works?
Tramadol, the active ingredient for Ultram is selective, weak OP3-receptor agonists. Opiate receptors are coupled with G-protein receptors and function as both positive and negative regulators of synaptic transmission via G-proteins that activate effector proteins. As the effector system is adenylate cyclase and cAMP located at the inner surface of the plasma membrane, opioids decrease intracellular cAMP by inhibiting adenylate cyclase. Subsequently, the release of nociceptive neurotransmitters such as substance P, GABA, dopamine, acetylcholine and nor-adrenaline is inhibited.
The analgesic properties of Tramadol can be attributed to norepinephrine and serotonin reuptake blockade in the CNS, which inhibits pain transmission in the spinal cord. The (+) enantiomer has higher affinity for the OP3 receptor and preferentially inhibits serotonin uptake and enhances serotonin release. The (-) enantiomer preferentially inhibits norepinephrine reuptake by stimulating alpha (2)-adrenergic receptors.
Dosage Information for Ultram 50mg:
Ultram is available as 50mg extended release tablets to be taken every 4 to 6 hours. You may take this medication with or without food. The dosage of this medication is based on the medical condition and response of the medication to treatment. Do not increase the dose, take the medication more frequently. Do not suddenly stop the medication. Reduce the dose of the medication and then stop it. Do not crush or chew the tablet; swallow it as a whole. However, some side effects are likely to occur while using this medication such as drowsiness, dizziness, tremor, headache, seizures, blurred vision, insomnia, vomiting, hiccups and upset stomach.
What are the safety precautions to be followed while using Ultram 50mg?
There are some precautionary measures to be kept in mind while using Ultram such as-
- Avoid use of this medication if you are hypersensitive to any of its active ingredient.
- Do not use this medication if you have any history of acute intermittent porphyria.
- Use the medication with extreme caution as it may cause drug dependence effect.
- It is a habit forming drug, so not indicated for use in patients with history of drug abuse.
- Avoid driving, doing any work, or operating any machinery that requires your alertness as this drug may cause dizziness.
- Avoid use of this medication during pregnancy and breastfeeding.
- Avoid intake of anti-allergic medication and any other anti-depressant medication while using this medication.
Where to buy Ultram 50mg?
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